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The critical importance of epigenetics in autoimmune-related skin diseases

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 43-57 doi: 10.1007/s11684-022-0980-8

Abstract: Autoimmune-related skin diseases are a group of disorders with diverse etiology and pathophysiology involvedGenetics and environmental factors may contribute to the development of these autoimmune disorders.this review, we discuss the most recent findings regarding the function of epigenetic mechanisms in autoimmune-relatedskin disorders, including systemic lupus erythematosus, bullous skin diseases, psoriasis, and systemic

Keywords： epigenetics     autoimmune-related skin diseases     DNA methylation     histone modifications     noncoding RNAs    

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Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 187-219 doi: 10.1007/s11684-015-0386-y

Abstract:

Autoimmune hepatitis is a chronic liver disease putatively caused by loss of tolerance to hepatocyte-specificAlthough autoimmune hepatitis occurs in childhood, this review focuses on disease in adults.Since many features also occur in other chronic liver diseases, these scoring systems aid evaluationTransplant recipients are at risk for recurrent autoimmune hepatitis in the allograft, and de

Keywords： autoimmune hepatitis     autoantibodies     diagnosis     immunological diseases     drug-induced liver injury     therapy    

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Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 10-19 doi: 10.1007/s11684-015-0388-9

Abstract: inflammatory diseases.Here, we summarize recent research progress on Th17 function in the development and pathogenesis of autoimmunediseases.molecule compounds to manipulate Th17 function for potential therapeutic application to treat human autoimmunediseases, including rheumatoid arthritis, systemic lupus erythematosus, Sj?

Keywords： IL-17     Th17 cells     RORγt     autoimmune diseases     posttranslational modification     inhibitors    

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γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 262-268 doi: 10.1007/s11684-017-0584-x

Abstract: distributional, and functional patterns and can rapidly respond to various insults and contribute to diverse diseasesγδ T cells play important roles in liver infection, non-alcoholic fatty liver disease, autoimmuneWe believe that determining the properties and functions of γδ T cells in liver diseasesenhances our understanding of the pathogenesis of liver diseases and is useful for the design of novelγδ T cell-based therapeutic regimens for liver diseases.

Keywords： γδT cells     liver infection     non-alcoholic fatty liver disease     autoimmune hepatitis     liver fibrosis and cirrhosis    

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NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 249-261 doi: 10.1007/s11684-018-0622-3

Abstract: Natural killer T cells play important roles in infections, tumors, autoimmune diseases, and metabolicdiseases.biology of natural killer T cells and their roles in hepatitis B virus and hepatitis C virus infection, autoimmuneliver diseases, alcoholic liver disease, nonalcoholic fatty liver disease, and hepatocellular carcinomaindicate the dynamic alteration in the role of natural killer T cells during the progression of liver diseases

Keywords： natural killer T cells     hepatitis B virus and hepatitis C virus infection     autoimmune liver diseases     alcoholic    

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Primary cilia in hard tissue development and diseases

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 657-678 doi: 10.1007/s11684-021-0829-6

Abstract: Hard tissue diseases have a serious effect on human survival and quality of life.Mutations in cilium-related genes result in a variety of developmental and even lethal diseases.In addition, the cilium-related diseases of hard tissue and the manifestations of mutant cilia in theWe believe that all the findings will help with the intervention and treatment of related hard tissuegenetic diseases.

Keywords： primary cilia     bone     mechanical sensing     hard tissue     cilium-related bone disease     tooth    

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Deformation analysis of shape memory polymer for morphing wing skin under airflow

Weilong YIN, Jingcang LIU, Jinsong LENG,

Frontiers of Mechanical Engineering 2009, Volume 4, Issue 4,   Pages 447-449 doi: 10.1007/s11465-009-0062-5

Abstract: The method for analyzing the out-of-plane deformation of a flexible skin under airflow is developed inthe present study is to investigate the out-of-plane deformation of the shape memory polymer (SMP) skinNumerical results show that the maximum out-of-plane displacement of the SMP skin increases with increasingWhen the SMP skin is heated to 53°C, the maximum out-of-plane displacement is about 7 mm.It decreases by 72%, when the SMP skin is applied with a uniform pre-strain of 0.1.

Keywords： aircraft     morphing     skin     shape memory polymer (SMP)     deformation     pre-strain    

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A Resilience Approach for Diagnosing and Predicting HBV-Related Diseases based on Blood Tests Article

Gege Hou,Yunru Chen,Xiaojing Liu,Dong Zhang,Zhimin Geng,Shubin Si

Engineering 2024, Volume 32, Issue 1,   Pages 174-185 doi: 10.1016/j.eng.2023.06.013

Abstract: hepatitis B virus (HBV) infection, which threatens global public health, is a major contributor to liver-relatedExaminations for liver diseases related to chronic HBV infection—including laboratory tests, ultrasoundsestablish an economical and effective diagnosis method in order to streamline the medical process for HBV-relateddiseases.thresholds, which can guide further research on preventing disease deterioration in critical states of these diseases

Keywords： HBV-related diseases     Functional resilience     Improve medical resource utilization     Critical states     Network    

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Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 534-548 doi: 10.1007/s11684-022-0953-y

Abstract: Autoimmune hepatitis (AIH) is a severe globally distributed liver disease that could occur at any age

Keywords： autoimmune hepatitis (AIH)     concanavalin A (Con A)     human menstrual blood-derived stem cells (MenSCs)    

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Hyperthermia on skin immune system and its application in the treatment of human papillomavirus-infectedskin diseases

Xinghua Gao, Hongduo Chen

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 1-5 doi: 10.1007/s11684-014-0309-3

Abstract: Hyperthermia has also been used to treat deep fungal, bacterial, and viral skin infections.We conducted a series of open or controlled trials to treat skin human papillomavirus infection by inducing

Keywords： hyperthermia     HPV     immune response     virus     tumor    

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Risk stratification system for skin and soft tissue infections after allogeneic hematopoietic stem cell

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 957-968 doi: 10.1007/s11684-021-0910-1

Abstract: Skin and soft tissue infections (SSTIs) refer to infections involving the skin, subcutaneous tissue,

Keywords： skin and soft tissue infections     hematopoietic stem cell transplantation     risk stratification system    

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Numerical study of thermal characteristics of double skin facade system with middle shade

Shaoning LIU, Xiangfei KONG, Hua YANG, Minchao FAN, Xin ZHAN

Frontiers in Energy 2021, Volume 15, Issue 1,   Pages 222-234 doi: 10.1007/s11708-017-0480-8

Abstract: A new shade combined with the double skin façade (DSF) system, called middle shade (MS), was introduced

Keywords： middle shade     position     thermal characteristics     double skin facade    

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Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 243-247 doi: 10.1007/s11684-012-0201-y

Abstract: Latent autoimmune diabetes in adults (LADA) is a subtype of autoimmune diabetes.Here, we aim to review and discuss the diagnostic criteria of latent autoimmune diabetes in adults.

Keywords： LADA     diagnostic criteria     autoantibodies     insulin independence     age of diagnosis    

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Moment-curvature relationship of FRP-concrete-steel double-skin tubular members

Mingxue LIU, Jiaru QIAN

Frontiers of Structural and Civil Engineering 2009, Volume 3, Issue 1,   Pages 25-31 doi: 10.1007/s11709-009-0012-7

Abstract: 3 specimens to study the flexural behavior of fiber reinforced polymer (FRP)-concrete-steel double-skin

Keywords： fiber reinforced polymer (FRP)     concrete     steel     double-skin tubular members (DSTMs)     moment-curvature curve    

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Analysis of effect of different construction methods of piles on the end effect on skin friction of piles

ZHOU Hongbo, CHEN Zhuchang

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 4,   Pages 458-463 doi: 10.1007/s11709-007-0062-7

Abstract: Based on the comparative analysis of end effect on skin friction of displacement-pile (driven pile),the end effect on skin friction of bored pile is studied.The end effect on skin friction between driven pile and bored pile is different and the end effect onskin friction of bored pile is reduce of skin friction in the soil layer adjacent to the pile end.The degradation degree of skin friction is deduced with the increase of the distance from pile end.

Keywords： distance     different     concept     additional     bottom    

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Title Author Date Type Operation

The critical importance of epigenetics in autoimmune-related skin diseases

Journal Article

Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Journal Article

Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Journal Article

γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Journal Article

NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Journal Article

Primary cilia in hard tissue development and diseases

Journal Article

Deformation analysis of shape memory polymer for morphing wing skin under airflow

Weilong YIN, Jingcang LIU, Jinsong LENG,

Journal Article

A Resilience Approach for Diagnosing and Predicting HBV-Related Diseases based on Blood Tests

Gege Hou,Yunru Chen,Xiaojing Liu,Dong Zhang,Zhimin Geng,Shubin Si

Journal Article

Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Journal Article

Hyperthermia on skin immune system and its application in the treatment of human papillomavirus-infectedskin diseases

Xinghua Gao, Hongduo Chen

Journal Article

Risk stratification system for skin and soft tissue infections after allogeneic hematopoietic stem cell

Journal Article

Numerical study of thermal characteristics of double skin facade system with middle shade

Shaoning LIU, Xiangfei KONG, Hua YANG, Minchao FAN, Xin ZHAN

Journal Article

Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Journal Article

Moment-curvature relationship of FRP-concrete-steel double-skin tubular members

Mingxue LIU, Jiaru QIAN

Journal Article

Analysis of effect of different construction methods of piles on the end effect on skin friction of piles

ZHOU Hongbo, CHEN Zhuchang

Journal Article